On December 5, 2024, the European Commission revised the Carcinogenic, Mutagenic, or toxic to Reproduction (CMR) substances list within REACH’s Annex XVII (Regulation (EC) No 1907/2006), introducing three key changes.
- Public Sale and Use Restrictions: The updated regulation strictly bans the public sale and use of Category 1A or 1B carcinogens, germ cell mutagens, or reproductive toxins, as detailed in Articles 28, 29, and 30 of Regulations (EC) No 1272/2008 and 1907/2006. It also imposes stringent controls on the concentration of these substances in mixtures.
- Annex XVII Appendices Expansion: The regulation adds substances to Appendices 2, 4, and 6 of Annex XVII, reflecting the inclusion of newly classified Category 1B CMR substances.
- Isopropylbenzene Use Exemptions: According to Regulation (EU) 2023/1132, from December 1, 2023, isopropylbenzene is not to be marketed or used in aviation fuel at concentrations of 0.1% w/w or higher for non-professional pilots. However, this does not apply to automotive fuel for non-professional drivers. Given the similarities between non-professional drivers and small aircraft pilots, and the fewer number of the latter, isopropylbenzene in aviation fuel is exempt from restrictions in Articles 28, 29, and 30 of Annex XVII to Regulation (EC) No 1907/2006.
These changes will become effective 20 days after publication and will be fully implemented by September 1, 2025. Despite the formal enforcement of the new Category 1B CMR substances provisions starting from September 1, 2025, the European Union urges operators to act proactively.
Annex XVII is amended as follows:
The following substances are to be incorporated into Appendix 2.
| مادہ | انڈیکس نمبر | EC نمبر | CAS نہیں |
| ‘diuron (ISO); 3-(3,4-dichlorophenyl)-1,1-dimethylurea | 006 015-00 9 | 206-354-4 | 330-54-1’ |
| ‘2,2′,6,6′-tetrabromo-4,4′-isopropylidenediphenol; tetrabromobisphenol-A | 604 074-00 0 | 201-236-9 | 79-94-7’ |
| ‘N,N-dimethyl-p-toluidine | 612 296-00 4 | 202-805-4 | 99-97-8’ |
| ‘4-nitrosomorpholine | 613 346-00 8 | - | 59-89-2’ |
| ‘4-methylimidazole | 613 349-00 4 | 212-497-3 | 822-36-6’ |
The following substance is to be incorporated into Appendix 4.
| مادہ | انڈیکس نمبر | EC نمبر | CAS نہیں |
| ‘dimethyl propylphosphonate | 015 208-00 7 | 242-555-3 | 18755-43-6’ |
The following substances are to be incorporated into Appendix 6.
| مادہ | انڈیکس نمبر | EC نمبر | CAS نہیں |
| ‘diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide | 015-203-00-ایکس۔ | 278-355-8 | 75980-60-8’ |
| ‘benzyl(diethylamino)diphenylphosphonium 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenolate | 015 204-00 5 | 479-100-5 | 577705-90-9’ |
| ‘benzyltriphenylphosphonium, salt with 4,4′-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis[phenol] (1:1) | 015 205-00 0 | 278-305-5 | 75768-65-9’ |
| ‘reaction mass of 4,4′-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol and benzyl(diethylamino)diphenylphosphonium 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenolate (1:1) | 015 206-00 6 | - | -’ |
| ‘dimethyl propylphosphonate | 015 208-00 7 | 242-555-3 | 18755-43-6’ |
| ‘dibutyltin maleate | 050 034-00 5 | 201-077-5 | 78-04-6’ |
| ‘dibutyltin oxide | 050 035-00 0 | 212-449-1 | 818-08-6’ |
| ‘reaction mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl) butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)-2-hydroxymethyl butane | 603 244-00 1 | - | -’ |
| ‘4,4′-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol; bisphenol AF | 604 099-00 7 | 216-036-7 | 1478-61-1’ |
| ‘1,4-Benzenediamine, N,N’-mixed Ph and tolyl derivs.; | 612 298-00 5 | 273-227-8 | 68953-84-4’ |
| ‘4-methylimidazole | 613 349-00 4 | 212-497-3 | 822-36-6’ |
The following substances are to be incorporated into Appendix 11.
| مادہ | تضحیک |
| ‘2. CumeneCAS No 98-82-8EC No 202-704-5 | As a substance on its own or as a constituent of other substances in either of the following: a. kerosene used as aviation fuel conforming to DEF STAN 91-091, ASTM specification D1655 or equivalent recognised standards and marketed under descriptions such as Jet-A, Jet-A1 or JP-(x); b. gasoline used as aviation fuel conforming to DEF STAN 91-090, ASTM D910, ASTM D7547, EN 228 or equivalent recognised standards.’ |
You can freely access the EU CMR substances list via the provided link on ChemRadar.
اگر آپ کو کوئی مدد درکار ہے یا کوئی سوال ہے تو، براہ کرم service@cirs-group.com کے ذریعے ہم سے رابطہ کریں۔
سے ماخذ CIRS
ڈس کلیمر: اوپر بیان کردہ معلومات cirs-group.com کی طرف سے علی بابا.com سے آزادانہ طور پر فراہم کی گئی ہے۔ Alibaba.com بیچنے والے اور مصنوعات کے معیار اور وشوسنییتا کے بارے میں کوئی نمائندگی اور ضمانت نہیں دیتا۔ Alibaba.com مواد کے کاپی رائٹ سے متعلق خلاف ورزیوں کی کسی بھی ذمہ داری کو واضح طور پر مسترد کرتا ہے۔
